hPSCs-derived Schwann cells serve for disease modeling and drug discovery

Abstract

In this issue, Majd et al. derive Schwann cells from human pluripotent stem cells (hPSCs), which can be used to study Schwann cell development and physiology and model diabetic neuropathy. hPSC-derived Schwann cells possess the molecular features of primary Schwann cells and are capable of myelination in vitro and in vivo.